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Gene Therapy Boosts Brain Repair for Demyelinating Diseases "We’ve developed a gene therapy to stimulate production of new oligodendrocytes from stem and progenitor cells — both of which can become more specialized cell types — that are resident in the adult central nervous system," says Benjamin Deverman, a postdoctoral fellow in biology at Caltech and lead author of the paper. "In other words, we’re using the brain’s own progenitor cells as a way to boost repair." Caltech researchers…

Gene Therapy Boosts Brain Repair for Demyelinating Diseases “We’ve developed a gene therapy to stimulate production of new oligodendrocytes from stem and progenitor cells – both of which can become.

Researchers Show Brain Activity Drives Dynamic Changes in Neural Fiber Insulation - NeuroscienceNews.com Sending neural impulses quickly down a long nerve fiber requires insulation with myelin, which is formed by a cell called an oligodendrocyte that wraps itself around a neuron. This illustration shows an oligodendrocyte myelinating several axons. Credit Holly Fischer.

Calling for Aid: Damaged Nerve Cells Communicate with Stem Cells

Myelinated nerves. A section through myelinated nerve fibers and Schwann cells. Myelin (green) is an insulating fatty layer that surrounds the nerve fibre (axon, black), increasing the speed at which nerve impulses travel.

BE_Myelinated nerves. A section through myelinated nerve fibers and Schwann cells. Myelin (green) is an insulating fatty layer that surrounds the nerve fibre (axon, black), increasing the speed at which nerve impulses travel.

cross section of a bundle of nerve fibers

A cross section of a bundle of nerve fibers. Axons (orange) are wrapped in myelin (purple); an extension of the membrane of glial cells. Myelin has high lipid content, and acts to insulate the axons, causing them to transmit nerve impulses much faster.

Biomedical illustration of an oligodendrocyte repairing damaged myelin sheaths of a motor neuron. Such damage exposes nerve fibers and disrupts the ability of the nerve to carry messages. It is associated with diseases such as diabetes and multiple sclerosis.

Biomedical illustration of an oligodendrocyte repairing damaged myelin sheaths of a motor neuron. Such damage exposes nerve fibers and disrupts the ability of the nerve to carry messages. It is associated with diseases such as diabetes and multiple sclerosis.

myelin sheaths, a covering over some of your brain's neurons, helps to speed information being passed. Multiple Sclerosis (MS) is a disease that affects this coating and causes serious problems for those who have it.

Neurons: Myelin sheaths, a covering over some of your brain's neurons, helps to speed information being passed. Multiple Sclerosis (MS) is a disease that affects this coating and causes serious problems for those who have it.

The image shows stained oligodendrocyte progenitor cells in the brain.

Scientists at Johannes Gutenberg University Mainz (JGU) in Germany have discovered a new signal pathway in the brain that plays an important role in learning and the processing of sensory input.

THE BRAIN’S SILENT MAJORITY

Neurons are the brain’s rock stars. But without the glial cells — astrocytes, microglia and oligodendrocytes — there would be no show at all. A diagram by Arne Hurty for Stanford Medicine Magazine Fall

BOBBY NEEL ADAMS age map

"Age Maps", some excellent photomontages between child portrait and adult portrait of a same person, created by photographer Bobby Neel Adams.